Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14438267 | 0.84 | SMN1; SMN2 (0.64) | SMN1; SMN2CYP1A2ALDH1A1LMNAHTT | |
| SCHEMBL8279786 | 0.83 | SMN1; SMN2 (0.63) | SMN1; SMN2CYP1A2ALDH1A1LMNAHTT | |
| SCHEMBL14591949 | 0.83 | SMN1; SMN2 (0.65) | SMN1; SMN2CYP1A2ALDH1A1LMNAHTT | |
| SCHEMBL2898452 | 0.81 | NOTUM (0.64) | SMN1; SMN2CYP1A2ALDH1A1LMNAHTT | |
| SCHEMBL1221306 | 0.81 | MAPT (0.66) | SMN1; SMN2CYP1A2ALDH1A1LMNAHTT | |
| SCHEMBL1566577 | 0.81 | SMN1; SMN2 (0.64) | SMN1; SMN2CYP1A2ALDH1A1LMNAHTT | |
| SCHEMBL1566524 | 0.81 | SMN1; SMN2 (0.63) | SMN1; SMN2CYP1A2ALDH1A1LMNAHTT | |
| SCHEMBL14452037 | 0.81 | POLB (0.68) | SMN1; SMN2CYP1A2ALDH1A1LMNAHTT | |
| SCHEMBL23397340 | 0.81 | NOTUM (0.62) | SMN1; SMN2CYP1A2ALDH1A1LMNAPOLB | |
| SCHEMBL6402396 | 0.80 | SMN1; SMN2 (0.77) | SMN1; SMN2CYP1A2ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197522-A1 | Dpp-iv inhibitors | SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197522-A1 | Dpp-iv inhibitors | DPP7, DPP4, DPP3 | SMN1; SMN2 4274/4885CYP1A2 1188/4885ALDH1A1 2070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.