Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14452004 | 0.83 | SMN1; SMN2 (0.69) | SMN1; SMN2CYP1A2ALDH1A1LMNAHTT | |
| SCHEMBL14438267 | 0.80 | SMN1; SMN2 (0.64) | SMN1; SMN2CYP1A2ALDH1A1LMNAHTT | |
| SCHEMBL14591949 | 0.78 | SMN1; SMN2 (0.65) | SMN1; SMN2CYP1A2ALDH1A1LMNAHTT | |
| SCHEMBL1566524 | 0.77 | SMN1; SMN2 (0.63) | SMN1; SMN2CYP1A2ALDH1A1LMNAHTT | |
| SCHEMBL1221306 | 0.77 | MAPT (0.66) | SMN1; SMN2CYP1A2ALDH1A1LMNAHTT | |
| SCHEMBL2898452 | 0.77 | NOTUM (0.64) | SMN1; SMN2CYP1A2ALDH1A1LMNAHTT | |
| SCHEMBL1566577 | 0.77 | SMN1; SMN2 (0.64) | SMN1; SMN2CYP1A2ALDH1A1LMNAHTT | |
| SCHEMBL28432486 | 0.75 | MAPT (0.89) | SMN1; SMN2CYP1A2ALDH1A1LMNAHTT | |
| SCHEMBL6402396 | 0.75 | SMN1; SMN2 (0.77) | SMN1; SMN2CYP1A2ALDH1A1LMNAHTT | |
| SCHEMBL15013473 | 0.75 | SMN1; SMN2 (0.56) | SMN1; SMN2CYP1A2ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005095343-A1 | DPP-IV INHIBITORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) | 2005-10-13 | — | — | WO | disclosed |