⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12808424 | 0.83 | — | — | |
| SCHEMBL14959960 | 0.82 | IDE (0.30) | — | |
| SCHEMBL14453033 | 0.80 | MAPT (0.32) | — | |
| SCHEMBL15275662 | 0.79 | — | — | |
| SCHEMBL10029727 | 0.79 | — | — | |
| SCHEMBL10000807 | 0.79 | — | — | |
| SCHEMBL12808503 | 0.78 | — | — | |
| SCHEMBL20924725 | 0.78 | — | — | |
| SCHEMBL12507145 | 0.75 | — | — | |
| SCHEMBL15583933 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2070530-B1 | Treatment of diseases associated with the use of antibiotics | MERCK SHARP & DOHME (US) | 2016-02-17 | — | — | EP | disclosed |
| US-20130274175-A1 | TREATMENT OF DISEASE ASSOCIATED WITH THE USE OF ANTIBIOTICS | OPTIMER PHARMACEUTICALS, INC. (US) | 2013-10-17 | — | — | US | disclosed |
| US-20130274175-A1 | TREATMENT OF DISEASE ASSOCIATED WITH THE USE OF ANTIBIOTICS | OPTIMER PHARMACEUTICALS, INC. (US) | 2013-10-17 | — | — | US | disclosed |
| US-20070173462-A1 | Treatment of diseases associated with the use of antibiotics | OPTIMER PHARMACEUTICALS, INC. (US) | 2007-07-26 | — | — | US | disclosed |
| US-20070173462-A1 | Treatment of diseases associated with the use of antibiotics | OPTIMER PHARMACEUTICALS, INC. (US) | 2007-07-26 | — | — | US | disclosed |