Sugi Predict
/ Targets
/ IDE
Top predicted compounds (top 20 by supporting neighbours, then confidence)
Clinical trials — most relevant to IDE by text similarity (a relevance ranking, not an exhaustive list)
| Trial | Phase | Status |
|---|
| Comparison of Glargine to Degludec Insulin Transition With or Without a Bridging Glargine Dose |
PHASE4 | COMPLETED |
| Growth Hormone and Glucose Metabolism |
PHASE4 | COMPLETED |
| China Post-approval Commitment (PAC) Study of Avalglucosidase Alfa in Participants With IOPD |
PHASE4 | RECRUITING |
| Extension Study of Idursulfase-IT Along With Elaprase in Children and Adults With Hunter Syndrome and Cognitive Impairment |
PHASE2/PHASE3 | ACTIVE_NOT_RECRUITING |
| Study of Intrathecal Idursulfase-IT Administered in Conjunction With Elaprase® in Pediatric Patients With Hunter Syndrome and Early Cognitive Impairment |
PHASE2/PHASE3 | COMPLETED |
| Safety and Efficacy of GS-100 Gene Therapy in Patients With NGLY1 Deficiency |
PHASE3 | ACTIVE_NOT_RECRUITING |
| Effect of a Multidomain Intervention Plus Turmeric on the Prevention of Cognitive Decline in People Over 55 Years of Age With Insulin Resistance. |
PHASE2/PHASE3 | ACTIVE_NOT_RECRUITING |
| Efficacy and Safety of Pegzilarginase in Patients With Arginase 1 Deficiency |
PHASE3 | COMPLETED |
| A Phase 2 Study of Cyclo-Z in Subjects With Type 2 Diabetes |
PHASE2 | COMPLETED |
| Development of NIC5-15 in the Treatment of Alzheimer's Disease |
PHASE2 | COMPLETED |
| A Single Site, Randomized, Double-blind, Placebo Controlled Trial of NIC5-15 in Subjects With Alzheimer's Disease |
PHASE2 | COMPLETED |
| Insulin-Sensitizing Anti-Inflammatory Small Molecule for Investigative Treatment of Dementia |
PHASE2 | COMPLETED |
| Safety Study to Assess Whether Proinsulin Peptide Injections Can Slow or Stop the Body Damaging Its Own Insulin-making Cells in the Pancreas in Patients Newly Diagnosed With Type 1 Diabetes |
PHASE1/PHASE2 | COMPLETED |
| Efficacy of SYR-472 in Subjects With Type 2 Diabetes Mellitus |
PHASE2 | COMPLETED |
| Study Assessing Potential Predictive Tumor Markers in Metastatic Colorectal Cancer |
PHASE2 | COMPLETED |
| Study to Evaluate the Safety, Tolerability, Efficacy and PK of IdeS in Kidney Transplantation |
PHASE2 | COMPLETED |
| Ambroxol Therapy for Patients With Type 1 Gaucher Disease and Suboptimal Response to Enzyme Replacement Therapy |
PHASE2 | COMPLETED |
| Intravitreal ERT to Prevent Retinal Disease Progression in Children With CLN2 |
PHASE1/PHASE2 | ACTIVE_NOT_RECRUITING |
| Efficacy and Safety of SYR-472 in Subjects With Type 2 Diabetes Mellitus |
PHASE2 | COMPLETED |
| Hyaluronidase Effect on Infusion Set Life |
PHASE1 | COMPLETED |
| First-in-Human Study of ISH0688: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics |
PHASE1 | NOT_YET_RECRUITING |
| Randomized, Double-blind, Crossover, Pharmacokinetic (PK) and Glucodynamic (GD) Study of Continuous Subcutaneous Insulin Infusion (CSII) in Participants With Type 1 Diabetes Mellitus (T1DM) |
PHASE1 | COMPLETED |
| A Trial Investigating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Subcutaneous NNC0123-0338 in Healthy Subjects and in Subjects With Type 1 Diabetes Mellitus |
PHASE1 | COMPLETED |
| Tauroursodeoxycholic Acid for Protease-inhibitor Associated Insulin Resistance |
nan | COMPLETED |
| Short Term Study of Recombinant Human Insulin-like Growth Factor I in Children With Hyperinsulinism |
nan | COMPLETED |
| Marker of Brain Insulin Resistance in AD Prognosis |
nan | NOT_YET_RECRUITING |
| Dose Ranging Study of Recombinant Human Insulin-like Growth Factor I in Children With Hyperinsulinism |
nan | COMPLETED |
| Acute Pancreatitis Targets (APT) Study |
nan | COMPLETED |
| Parent Intervention to Prevent Disordered Eating in Children With Type 1 Diabetes |
nan | COMPLETED |
| Defining the Molecular and Physiological Mechanisms of Pancreatic Islet Cell Dysfunction Which Lead to Type 2 Diabetes |
nan | COMPLETED |
Related proteins — ESM-2 sequence neighbours (a IDE binder may also engage these)