Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 3/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13632415 | 0.93 | NPC1 (0.44) | NPC1RAB9AMAPTGFERMCL1 | |
| SCHEMBL12190329 | 0.87 | TAAR1 (0.41) | NPC1RAB9ATP53SMN1; SMN2TAAR1 | |
| SCHEMBL14453078 | 0.86 | RARB (0.48) | NPC1RAB9AMAPTGFERRARB | |
| SCHEMBL28019896 | 0.81 | GCGR (0.43) | NPC1RAB9AMAPTGFERTP53 | |
| SCHEMBL18416779 | 0.81 | CYP17A1 (0.44) | NPC1RAB9AMAPTGFERMCL1 | |
| SCHEMBL16488492 | 0.81 | RARB (0.42) | NPC1RAB9AMAPTGFERMCL1 | |
| SCHEMBL16258034 | 0.81 | CYP17A1 (0.44) | NPC1RAB9AMAPTGFERMCL1 | |
| SCHEMBL15965523 | 0.81 | RARB (0.42) | NPC1RAB9AMAPTGFERMCL1 | |
| SCHEMBL16377212 | 0.81 | RARB (0.49) | NPC1RAB9AMAPTGFERMCL1 | |
| SCHEMBL9494601 | 0.81 | RARB (0.56) | RAB9AMAPTRARBRARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7258903-B2 | Fast switching liquid crystal compositions for use in bistable liquid crystal devices | MERCK PATENT GMBH (DE) | 2007-08-21 | — | — | US | disclosed |