Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13609919 | 0.86 | ALDH1A1 (0.44) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL12294059 | 0.85 | TSHR (0.44) | TSHRNAAAHCAR2RAD52NPSR1 | |
| SCHEMBL12292491 | 0.85 | TSHR (0.44) | TSHRNAAAHCAR2RAD52NPSR1 | |
| SCHEMBL12292487 | 0.85 | TSHR (0.44) | TSHRNAAAHCAR2RAD52NPSR1 | |
| SCHEMBL12292861 | 0.82 | MEN1 (0.41) | TSHRNAAAHCAR2RAD52NPSR1 | |
| SCHEMBL13609916 | 0.82 | MEN1 (0.41) | TSHRNAAAHCAR2RAD52NPSR1 | |
| SCHEMBL12294062 | 0.82 | MEN1 (0.41) | TSHRNAAAHCAR2RAD52NPSR1 | |
| SCHEMBL14261087 | 0.82 | MEN1 (0.41) | TSHRNAAAHCAR2RAD52NPSR1 | |
| SCHEMBL12382057 | 0.82 | TSHR (0.41) | TSHRNAAAHCAR2RAD52NPSR1 | |
| SCHEMBL12292872 | 0.82 | MEN1 (0.41) | TSHRNAAAHCAR2RAD52NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244859-B2 | Method for producing δ-aminopentadienoate derivatives | FUJIFILM CORPORATION (JP) | 2007-07-17 | — | — | US | disclosed |