Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | PHGDH | O43175 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8223139 | 0.82 | TSHR (0.48) | TSHRHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL8230258 | 0.80 | TSHR (0.49) | TSHRHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL14456691 | 0.80 | TSHR (0.48) | TSHRHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL14456685 | 0.79 | ALDH1A1 (0.57) | TSHRHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL14456744 | 0.79 | KMT2A (0.56) | TSHRALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL8420394 | 0.78 | KMT2A (0.55) | TSHRHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL14469623 | 0.77 | TSHR (0.48) | TSHRHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL8223179 | 0.76 | TSHR (0.49) | TSHRHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL14456705 | 0.76 | KDM4E (0.53) | TSHRHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL8420393 | 0.76 | ALDH1A1 (0.44) | TSHRHPGDALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |