Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14456892 | 0.89 | MEN1 (0.63) | MEN1KMT2ATSHRALDH1A1L3MBTL1 | |
| SCHEMBL13588422 | 0.86 | MEN1 (0.72) | SMN1; SMN2MEN1KMT2ATSHRKDM4E | |
| SCHEMBL14456748 | 0.84 | KMT2A (0.73) | SMN1; SMN2MEN1KMT2ATSHRKDM4E | |
| SCHEMBL14456826 | 0.83 | L3MBTL1 (0.57) | MEN1KMT2ATSHRL3MBTL1CYP3A4 | |
| SCHEMBL14456755 | 0.83 | CYP3A4 (0.65) | SMN1; SMN2MEN1KMT2ATSHRKDM4E | |
| SCHEMBL14456802 | 0.82 | L3MBTL1 (0.60) | MEN1KMT2ATSHRALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1449121 | 0.81 | SMN1; SMN2 (0.59) | SMN1; SMN2MEN1KMT2ATSHRKDM4E | |
| SCHEMBL14456891 | 0.80 | HIF1A (0.60) | MEN1KMT2ATSHRL3MBTL1CYP3A4 | |
| SCHEMBL14456786 | 0.80 | MEN1 (0.63) | MEN1KMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL13003531 | 0.80 | ACKR3 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |
| US-7238688-B2 | Piperidine compounds | SCHERING CORPORATION (US) | 2007-07-03 | — | — | US | disclosed |