SCHEMBL1445720

SCHEMBL1445720

C=CC[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.47
LGALS1 P09382 2/20 0.47
LGALS3 P17931 2/20 0.47
LGALS9 O00182 1/20 0.47
LGALS8 O00214 1/20 0.47
SLC2A1 P11166 1/20 0.39
MAPT P10636 1/20 0.39
CA12 O43570 3/20 0.38
CA1 P00915 3/20 0.38
CA2 P00918 3/20 0.38
CA9 Q16790 3/20 0.38
OGA O60502 1/20 0.37
HEXB P07686 1/20 0.37
PYGB P11216 4/20 0.37
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6297129 1.00 L3MBTL1 (0.47) L3MBTL1LGALS1LGALS3LGALS9LGALS8
SCHEMBL15820316 1.00 L3MBTL1 (0.47) L3MBTL1LGALS1LGALS3LGALS9LGALS8
SCHEMBL1445509 1.00 L3MBTL1 (0.47) L3MBTL1LGALS1LGALS3LGALS9LGALS8
SCHEMBL12599990 1.00 L3MBTL1 (0.47) L3MBTL1LGALS1LGALS3LGALS9LGALS8
SCHEMBL1445770 1.00 L3MBTL1 (0.47) L3MBTL1LGALS1LGALS3LGALS9LGALS8
SCHEMBL1445306 1.00 L3MBTL1 (0.47) L3MBTL1LGALS1LGALS3LGALS9LGALS8
SCHEMBL4796941 1.00 L3MBTL1 (0.47) L3MBTL1LGALS1LGALS3LGALS9LGALS8
SCHEMBL29249548 0.98 L3MBTL1 (0.44) L3MBTL1LGALS1LGALS3LGALS9LGALS8
SCHEMBL17087884 0.98 L3MBTL1 (0.44) L3MBTL1LGALS1LGALS3LGALS9LGALS8
SCHEMBL16056055 0.98 L3MBTL1 (0.44) L3MBTL1LGALS1LGALS3LGALS9LGALS8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120178913-A1 OLEFIN METATHESIS REACTIONS OF AMINO ACIDS, PEPTIDES AND PROTEINS CONTAINING ALLYL SULFIDE GROUPS ISIS INNOVATION LIMITED (GB) 2012-07-12 US disclosed
EP-2288614-A1 OLEFIN METATHESIS REACTIONS OF AMINO ACIDS, PEPTIDES AND PROTEINS CONTAINING ALLYL SULFIDE GROUPS ISIS Innovation Limited (GB) 2011-03-02 EP disclosed
WO-2009147414-A1 OLEFIN METATHESIS REACTIONS OF AMINO ACIDS, PEPTIDES AND PROTEINS CONTAINING ALLYL SULFIDE GROUPS ISIS INNOVATION LIMITED (GB) 2009-12-10 WO disclosed
WO-2005000873-A1 PREPARATION OF GLYCOSYLATED AMINO ACIDS, PROTEINS AND PEPTIDES VIA OLEFIN METATHESIS REACTIONS ISIS INNOVATION LIMITED (GB) 2005-01-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120178913-A1 OLEFIN METATHESIS REACTIONS OF AMINO ACIDS, PEPTIDES AND PROTEINS CONTAINING ALLYL SULFIDE GROUPS MAX, PTMS, OSBP L3MBTL1 1453/4885LGALS1 2780/4885LGALS3 3462/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.