Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 11/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 6/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14458017 | 0.85 | AR (0.43) | DDB1CRBNKCNH2 | |
| SCHEMBL13701090 | 0.83 | KCNH2 (0.55) | MAOBMAOAKCNH2RAB9A | |
| SCHEMBL22201142 | 0.80 | TP53 (0.51) | DDB1CRBNKMT2A | |
| SCHEMBL14458006 | 0.80 | TP53 (0.51) | DDB1CRBNKMT2A | |
| SCHEMBL14458018 | 0.79 | CRBN (0.40) | DDB1CRBNNPC1KMT2A | |
| SCHEMBL27928981 | 0.74 | HTT (0.51) | CRBNMAOBMAOANPC1RAB9A | |
| SCHEMBL19134705 | 0.72 | MAOB (0.59) | EGFRMAOBAPPMAOANR4A2 | |
| SCHEMBL14458014 | 0.72 | ESR2 (0.51) | — | |
| SCHEMBL14458012 | 0.71 | POLB (0.57) | DDB1CRBNKMT2A | |
| SCHEMBL4148437 | 0.71 | GRIN2B (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250521-B2 | Method for production of Δ1-pyrrolines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT | 2007-07-31 | — | — | US | disclosed |
| US-7250521-B2 | Method for production of Δ1-pyrrolines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT | 2007-07-31 | — | — | US | disclosed |