Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4148437 | 0.89 | GRIN2B (0.49) | GRIN2BGRM2MMP2MMP9L3MBTL1 | |
| SCHEMBL5889322 | 0.89 | GRIN2B (0.49) | GRIN2BGRM2MMP2MMP9L3MBTL1 | |
| SCHEMBL5620504 | 0.85 | GRIN2B (0.46) | GRIN2BDDB1CRBNL3MBTL1 | |
| SCHEMBL14458013 | 0.85 | EGFR (0.49) | KCNH2DDB1CRBN | |
| SCHEMBL13701090 | 0.80 | KCNH2 (0.55) | KCNH2GSTP1 | |
| SCHEMBL14458018 | 0.79 | CRBN (0.40) | DDB1CRBN | |
| SCHEMBL13945021 | 0.78 | PDE4A (0.40) | GRIN2BKCNH2DDB1CRBNMMP14 | |
| SCHEMBL14474703 | 0.78 | PDE4A (0.40) | GRIN2BKCNH2DDB1CRBNMMP14 | |
| SCHEMBL14063609 | 0.73 | DRD2 (0.40) | GRIN2B | |
| SCHEMBL27928981 | 0.72 | HTT (0.51) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250521-B2 | Method for production of Δ1-pyrrolines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT | 2007-07-31 | — | — | US | disclosed |
| US-7250521-B2 | Method for production of Δ1-pyrrolines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT | 2007-07-31 | — | — | US | disclosed |