Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.51 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.50 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.50 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.50 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.50 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.50 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12298244 | 0.91 | CSNK2A1 (0.62) | ALOX5MAPTMEN1KMT2ARAB9A | |
| SCHEMBL14458550 | 0.89 | CYP1A1 (0.59) | ALOX5MAPTMEN1KMT2ARAB9A | |
| SCHEMBL10072680 | 0.85 | MEN1 (0.61) | ALOX5MAPTMEN1KMT2ARAB9A | |
| SCHEMBL12298058 | 0.85 | ALOX5 (0.64) | ALOX5MAPTMEN1KMT2ARAB9A | |
| SCHEMBL12298224 | 0.84 | MEN1 (0.69) | ALOX5MAPTMEN1KMT2ARAB9A | |
| SCHEMBL12298079 | 0.83 | CYP1A1 (0.63) | ALOX5MAPTMEN1KMT2ARAB9A | |
| SCHEMBL12298369 | 0.83 | MEN1 (0.61) | ALOX5MAPTMEN1KMT2ARAB9A | |
| SCHEMBL12298132 | 0.82 | CSNK2A1 (0.65) | ALOX5MAPTMEN1KMT2ARAB9A | |
| SCHEMBL7119104 | 0.81 | ALOX5 (0.60) | ALOX5MAPTMEN1KMT2ARAB9A | |
| SCHEMBL12297735 | 0.81 | CYP1A1 (0.58) | ALOX5MAPTMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244739-B2 | Compounds and uses thereof in modulating amyloid beta | TORREYPINES THERAPEUTICS, INC. (US) | 2007-07-17 | — | — | US | disclosed |
| US-7244739-B2 | Compounds and uses thereof in modulating amyloid beta | TORREYPINES THERAPEUTICS, INC. (US) | 2007-07-17 | — | — | US | disclosed |