Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | ACP1 | P24666 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12531999 | 0.76 | HTR2C (0.51) | MCHR1HTR2CDRD3KCNH2HTR2A | |
| SCHEMBL12531977 | 0.75 | LTA4H (0.52) | MCHR1HTR2CKCNH2HTR2AHTR2B | |
| SCHEMBL12532102 | 0.73 | MCHR1 (0.47) | MCHR1HTR2CDRD2DRD3KCNH2 | |
| SCHEMBL12531980 | 0.73 | MCHR1 (0.64) | MCHR1 | |
| SCHEMBL12531976 | 0.73 | MCHR1 (0.54) | MCHR1HTR2CDRD2DRD3 | |
| SCHEMBL12531954 | 0.72 | MCHR1 (0.62) | MCHR1HTR2CDRD3KCNH2SIGMAR1 | |
| SCHEMBL12531994 | 0.72 | HTR2C (0.65) | MCHR1HTR2CDRD3KCNH2HTR2A | |
| SCHEMBL12531987 | 0.72 | TMEM97 (0.50) | MCHR1HTR2CDRD2DRD3SIGMAR1 | |
| SCHEMBL4899236 | 0.71 | HTR2C (0.56) | MCHR1HTR2CKCNH2HTR2AHTR2B | |
| SCHEMBL12532001 | 0.71 | MCHR1 (0.57) | MCHR1HTR2CDRD3KCNH2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007092416-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR-1 ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-08-16 | — | — | WO | disclosed |