Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.77 |
| ▸ | ICMT | O60725 | 2/20 | 0.67 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.60 |
| ▸ | CNR2 | P34972 | 7/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8143904 | 0.99 | CDC25A (0.74) | CDC25AICMTOXER1CNR2ADRA1D | |
| SCHEMBL13061260 | 0.89 | CDC25A (0.60) | CDC25AICMTOXER1CNR2ADRA1D | |
| SCHEMBL9700510 | 0.87 | CDC25A (1.00) | CDC25AICMTCNR2KDM4EALDH1A1 | |
| SCHEMBL15747697 | 0.87 | CDC25A (1.00) | CDC25AICMTCNR2KDM4EALDH1A1 | |
| SCHEMBL2429439 | 0.85 | CDC25A (0.97) | CDC25AICMTCNR2KDM4EALDH1A1 | |
| SCHEMBL9210193 | 0.84 | PLK1 (0.58) | CDC25AOXER1MCL1CREBBP | |
| SCHEMBL10967590 | 0.83 | CDC25A (0.66) | CDC25AICMTCNR2CNR1 | |
| SCHEMBL8960035 | 0.83 | CDC25A (0.60) | CDC25AICMTOXER1ADRA1DADRA1A | |
| SCHEMBL13061259 | 0.82 | PLK1 (0.57) | CDC25AADRA1DADRA1AMCL1CREBBP | |
| SCHEMBL31370560 | 0.82 | PLK1 (0.57) | CDC25ACNR2ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244763-B2 | Compounds that modulate PPAR activity and methods of preparation | WARNER LAMBERT COMPANY LLC (US) | 2007-07-17 | — | — | US | disclosed |