Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 1.00 |
| ▸ | ICMT | O60725 | 2/20 | 0.79 |
| ▸ | CNR2 | P34972 | 9/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 2/20 | 0.56 |
| ▸ | PLK1 | P53350 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700510 | 1.00 | CDC25A (1.00) | CDC25AICMTCNR2MCL1KDM4E | |
| SCHEMBL2429439 | 0.99 | CDC25A (0.97) | CDC25AICMTCNR2MCL1KDM4E | |
| SCHEMBL15747729 | 0.94 | CDC25A (0.90) | CDC25AICMTCNR2MCL1KDM4E | |
| SCHEMBL15747715 | 0.89 | CDC25A (0.80) | CDC25AICMTCNR2MCL1KDM4E | |
| SCHEMBL11893393 | 0.88 | ICMT (1.00) | CDC25AICMT | |
| SCHEMBL14459557 | 0.87 | CDC25A (0.77) | CDC25AICMTCNR2MCL1KDM4E | |
| SCHEMBL3667313 | 0.86 | ICMT (0.97) | CDC25AICMTCNR1 | |
| SCHEMBL17102877 | 0.86 | CDC25A (0.75) | CDC25AICMTCNR2CNR1 | |
| SCHEMBL15747719 | 0.86 | CDC25A (0.75) | CDC25AICMTCNR2CNR1 | |
| SCHEMBL8143904 | 0.85 | CDC25A (0.74) | CDC25AICMTCNR2MCL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12139459-B2 | Enhancer of fertilization function of sperm | TOHOKU UNIVERSITY (JP) | 2024-11-12 | — | — | US | disclosed |
| WO-2023238894-A1 | ANTIVIRAL AGENT | 国立大学法人東北大学 | 2023-12-14 | — | — | WO | disclosed |
| US-20220106270-A1 | ENHANCER OF FERTILIZATION FUNCTION OF SPERM | KAKE EDUCATIONAL INSTITUTION (JP) | 2022-04-07 | — | — | US | disclosed |
| US-11147796-B2 | Agent for preventing or ameliorating hearing impairment | TOHOKU UNIVERSITY (JP) | 2021-10-19 | — | — | US | disclosed |
| US-11147796-B2 | Agent for preventing or ameliorating hearing impairment | TOHOKU UNIVERSITY (JP) | 2021-10-19 | — | — | US | disclosed |
| US-10869858-B2 | Therapeutic agent for amyotrophic disorders | TOHOKU UNIVERSITY (JP) | 2020-12-22 | — | — | US | disclosed |
| US-10869858-B2 | Therapeutic agent for amyotrophic disorders | TOHOKU UNIVERSITY (JP) | 2020-12-22 | — | — | US | disclosed |
| US-10463647-B2 | Erythropoietin expression promoter | TOHOKU UNIVERSITY (JP) | 2019-11-05 | — | — | US | disclosed |
| US-10463647-B2 | Erythropoietin expression promoter | TOHOKU UNIVERSITY (JP) | 2019-11-05 | — | — | US | disclosed |
| US-20190224165-A1 | Agent for Preventing or Ameliorating Hearing Impairment | TOHOKU UNIVERSITY (JP) | 2019-07-25 | — | — | US | disclosed |
| US-10004718-B2 | Erythropoietin expression promoter | TOHOKU UNIVERSITY (JP) | 2018-06-26 | — | — | US | disclosed |
| US-10004718-B2 | Erythropoietin expression promoter | TOHOKU UNIVERSITY (JP) | 2018-06-26 | — | — | US | disclosed |
| US-10004718-B2 | Erythropoietin expression promoter | TOHOKU UNIVERSITY (JP) | 2018-06-26 | — | — | US | disclosed |
| US-20150353489-A1 | Erythropoietin Expression Promoter | KANAGAWA PREFECTURAL HOSPITAL ORGANIZATION KANAGAWA CHILDREN'S MEDICAL CENTER (JP) | 2015-12-10 | — | — | US | disclosed |
| US-20150353489-A1 | Erythropoietin Expression Promoter | KANAGAWA PREFECTURAL HOSPITAL ORGANIZATION KANAGAWA CHILDREN'S MEDICAL CENTER (JP) | 2015-12-10 | — | — | US | disclosed |
| US-20150353489-A1 | Erythropoietin Expression Promoter | KANAGAWA PREFECTURAL HOSPITAL ORGANIZATION KANAGAWA CHILDREN'S MEDICAL CENTER (JP) | 2015-12-10 | — | — | US | disclosed |
| EP-2923700-A1 | ERYTHROPOIETIN EXPRESSION PROMOTER | Tohoku University (JP) | 2015-09-30 | — | — | EP | disclosed |
| EP-2923700-A1 | ERYTHROPOIETIN EXPRESSION PROMOTER | Tohoku University (JP) | 2015-09-30 | — | — | EP | disclosed |
| CN-104936591-A | Erythropoietin expression promoter | UNIV TOHOKU NAT UNIV CORP | 2015-09-23 | — | — | CN | disclosed |
| WO-2014080640-A1 | ERYTHROPOIETIN EXPRESSION PROMOTER | 国立大学法人東北大学 (JP) | 2014-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12139459-B2 | Enhancer of fertilization function of sperm | CATSPER1, NASP, ZP1 | CDC25A 3493/4885ICMT 2177/4885CNR2 3607/4885 |
| US-11147796-B2 | Agent for preventing or ameliorating hearing impairment | SLC26A4, OTC, SLC25A20 | CDC25A 3942/4885ICMT 1421/4885CNR2 3704/4885 |
| US-20150353489-A1 | Erythropoietin Expression Promoter | EPOR, NFE2L2, FOXO1 | CDC25A 1969/4885ICMT 3976/4885CNR2 3518/4885 |
| US-20220106270-A1 | ENHANCER OF FERTILIZATION FUNCTION OF SPERM | CATSPER1, NASP, ZP1 | CDC25A 3493/4885ICMT 2177/4885CNR2 3607/4885 |
| US-20190224165-A1 | Agent for Preventing or Ameliorating Hearing Impairment | SLC26A4, OTC, SLC25A20 | CDC25A 3942/4885ICMT 1421/4885CNR2 3704/4885 |
| US-10869858-B2 | Therapeutic agent for amyotrophic disorders | SMN1; SMN2, MYOF, MUSK | CDC25A 4484/4885ICMT 4858/4885CNR2 4172/4885 |
| US-10004718-B2 | Erythropoietin expression promoter | EPOR, NFE2L2, FOXO1 | CDC25A 1969/4885ICMT 3976/4885CNR2 3518/4885 |
| US-10463647-B2 | Erythropoietin expression promoter | EPOR, NFE2L2, FOXO1 | CDC25A 1969/4885ICMT 3976/4885CNR2 3518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.