Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 4/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.54 |
| ▸ | RELA | Q04206 | 4/20 | 0.54 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4713242 | 1.00 | NFKB1 (0.54) | NFKB1NFKB2RELABTKCTSK | |
| SCHEMBL4713238 | 1.00 | NFKB1 (0.54) | NFKB1NFKB2RELABTKCTSK | |
| SCHEMBL4713236 | 1.00 | NFKB1 (0.54) | NFKB1NFKB2RELABTKCTSK | |
| SCHEMBL14459580 | 1.00 | NFKB1 (0.54) | NFKB1NFKB2RELABTKCTSK | |
| SCHEMBL6258791 | 0.90 | NFKB1 (0.51) | NFKB1NFKB2RELABTKCTSK | |
| SCHEMBL6258795 | 0.90 | NFKB1 (0.51) | NFKB1NFKB2RELABTKCTSK | |
| SCHEMBL4714079 | 0.87 | NFKB1 (0.54) | NFKB1NFKB2RELABTKCTSK | |
| SCHEMBL4714074 | 0.87 | NFKB1 (0.54) | NFKB1NFKB2RELABTKCTSK | |
| SCHEMBL4714078 | 0.87 | NFKB1 (0.54) | NFKB1NFKB2RELABTKCTSK | |
| SCHEMBL5601052 | 0.85 | NFKB1 (0.55) | NFKB1NFKB2RELABTKCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262215-B2 | N-carbacycle monosubstituted indolocarbazoles as protein kinase inhibitors | NAD AG (DE) | 2007-08-28 | — | — | US | disclosed |