Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 4/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL751062 | 0.81 | SLC1A2 (0.71) | SLC1A3SLC1A2SLC1A1CA2MAPK1 | |
| SCHEMBL15217711 | 0.78 | SLC1A2 (0.68) | SLC1A3SLC1A2SLC1A1CA2MAPK1 | |
| SCHEMBL4856341 | 0.78 | SLC1A2 (0.68) | SLC1A3SLC1A2SLC1A1CA2MAPK1 | |
| SCHEMBL13317543 | 0.78 | SLC1A2 (0.68) | SLC1A3SLC1A2SLC1A1CA2MAPK1 | |
| SCHEMBL17624904 | 0.78 | TSHR (0.47) | SLC1A3SLC1A2SLC1A1CA2USP2 | |
| SCHEMBL807054 | 0.77 | SLC1A3 (0.60) | SLC1A3SLC1A2SLC1A1CA2MAPK1 | |
| SCHEMBL12191525 | 0.77 | SLC1A3 (0.60) | SLC1A3SLC1A2SLC1A1CA2MAPK1 | |
| SCHEMBL322526 | 0.77 | SLC1A3 (0.60) | SLC1A3SLC1A2SLC1A1CA2MAPK1 | |
| SCHEMBL27352372 | 0.75 | SLC1A3 (0.48) | SLC1A3SLC1A2SLC1A1CA2MAPK1 | |
| SCHEMBL1716335 | 0.75 | SLC1A3 (0.58) | SLC1A3SLC1A2SLC1A1CA2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079406-A1 | SMALL MOLECULE INHIBITORS OF PDZ INTERACTIONS | ARBOR VITA CORPORATION (US) | 2007-07-12 | — | — | WO | disclosed |