SCHEMBL144607

SCHEMBL144607

CC(Cc1cccc(CC(C)c2ccc(O)cc2)c1)c1ccc(O)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 9/20 0.71
ESR2 Q92731 8/20 0.71
TAAR1 Q96RJ0 3/20 0.47
SLC6A2 P23975 3/20 0.47
PDCD1 Q15116 1/20 0.45
CD274 Q9NZQ7 1/20 0.45
MIF P14174 1/20 0.43
LMNA P02545 2/20 0.41
ADRA1A P35348 2/20 0.41
OPRM1 P35372 2/20 0.41
DRD3 P35462 2/20 0.41
SLC6A3 Q01959 2/20 0.41
CYP1A2 P05177 1/20 0.41
PGR P06401 1/20 0.41
CHRM2 P08172 1/20 0.41
CYP3A4 P08684 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
AR P10275 1/20 0.41
CYP2D6 P10635 1/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22031056 0.93 ESR1 (0.67) ESR1ESR2TAAR1SLC6A2PDCD1
SCHEMBL925617 0.90 ESR1 (0.80) ESR1ESR2TAAR1SLC6A2PDCD1
SCHEMBL25380112 0.90 ESR1 (0.73) ESR1ESR2TAAR1SLC6A2OPRM1
SCHEMBL25139430 0.88 ESR1 (0.61) ESR1ESR2TAAR1SLC6A2PDCD1
SCHEMBL1128548 0.88 ESR1 (0.61) ESR1ESR2TAAR1SLC6A2PDCD1
SCHEMBL28217880 0.86 ESR1 (0.81) ESR1ESR2TAAR1SLC6A2PDCD1
SCHEMBL1602384 0.86 ESR1 (0.81) ESR1ESR2TAAR1SLC6A2PDCD1
Ammonia Solution, Strong SCHEMBL8865775 0.85 ESR1 (0.78) ESR1ESR2TAAR1SLC6A2LMNA
SCHEMBL296781 0.84 ESR1 (1.00) ESR1ESR2TAAR1SLC6A2PDCD1
SCHEMBL1171038 0.84 ESR1 (1.00) ESR1ESR2TAAR1SLC6A2PDCD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3009 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3822299-B1 BIO-BASED POLYCARBONATE ESTER RESIN FOR EYEGLASS FRAME SK CHEMICALS CO LTD (KR) 2026-02-18 EP claimed
US-12391795-B2 Polymerizable composition, and copolycarbonate ester and method for producing same SK CHEMICALS CO., LTD. (KR) 2025-08-19 US claimed
US-12202994-B2 Thermochromic pigment compositions SOCIETE BIC (FR) 2025-01-21 US claimed
US-20240409677-A1 THERMOSETTING RESIN, COMPOSITION, UNCURED MOLDED BODY, PARTIALLY CURED MOLDED BODY, CURED MOLDED BODY, AND METHOD FOR PRODUCING THERMOSETTING RESIN KANEKA CORPORATION (JP) 2024-12-12 US claimed
US-20240400761-A1 HEAT-CURABLE RESIN, COMPOSITION, UNCURED MOLDED OBJECT, PARTLY CURED MOLDED OBJECT, CURED MOLDED OBJECT, AND METHOD FOR PRODUCING HEAT-CURABLE RESIN KANEKA CORPORATION (JP) 2024-12-05 US claimed
US-12139626-B2 Irreversibly erasable ink composition having a discoloration agent SOCIéTé BIC (FR) 2024-11-12 US claimed
EP-4424734-A1 THERMOSETTING RESIN, COMPOSITION, UNCURED MOLDED BODY, PARTIALLY CURED MOLDED BODY, CURED MOLDED BODY, AND METHOD FOR PRODUCING THERMOSETTING RESIN Kaneka Corporation (JP) 2024-09-04 EP claimed
US-12043596-B2 Thermochromic pigment compositions SOCIETE BIC (FR) 2024-07-23 US claimed
CN-115433350-B Preparation method of hyperbranched polysiloxane copolycarbonate 聊城鲁西聚碳酸酯有限公司 2024-05-24 CN claimed
US-11920047-B2 Method for preparing thermochromic water-based gel ink compositions, and thermochromic water-based gel ink compositions thereof SOCIéTé BIC (FR) 2024-03-05 US claimed
US-20040077820-A1 Method of making polycarbonate GENERAL ELECTRIC COMPANY 2004-04-22 US claimed
US-20040039145-A1 Method of preparing transparent silicone-containing copolycarbonates GENERAL ELECTRIC COMPANY 2004-02-26 US claimed
US-6657038-B1 Melt condensation copolymerization of dihydroxyaromatic compounds and diphenyl carbonate derivative in presence of metal hydroxide and quaternary phosphonium salt GENERAL ELECTRIC COMPANY 2003-12-02 US claimed
US-6600004-B1 Preparing polyestercarbonates is presented in which a mixture of at least one activated diaryl carbonate is reacted under melt polymerization conditions with at least one aromatic dihydroxy compound together with at least one dicarboxylic GENERAL ELECTRIC COMPANY 2003-07-29 US claimed
US-6518391-B1 Method of polycarbonate preparation by solid state polymerization GENERAL ELECTRIC COMPANY 2003-02-11 US claimed
US-6433126-B1 USING AROMATIC ALCOHOLS; BULK POLYMERIZATION GENERAL ELECTRIC COMPANY 2002-08-13 US claimed
US-6248859-B1 CONTAINING SPIROBIINDANE UNITS; OPTICAL DATA STORAGE MEDIA GENERAL ELECTRIC COMPANY 2001-06-19 US claimed
EP-0154336-B1 THERMOSENSITIVE RECORDING SHEET JUJO PAPER CO., LTD. (JP) 1988-10-26 EP claimed
US-4573062-A HYDROXYBENZ/YLOXYBENZOIC ACID COLOR DEVELOPER AND LEUCO DYE JUJO PAPER CO., LTD. (JP) 1986-02-25 US claimed
EP-0154336-A2 Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1985-09-11 EP claimed