SCHEMBL925617

SCHEMBL925617

CC(Cc1cc(CC(C)c2ccc(O)cc2)cc(CC(C)c2ccc(O)cc2)c1)c1ccc(O)cc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 13/20 0.80
ESR2 Q92731 12/20 0.80
PDCD1 Q15116 1/20 0.50
CD274 Q9NZQ7 1/20 0.50
MIF P14174 1/20 0.47
TAAR1 Q96RJ0 3/20 0.47
SLC6A2 P23975 2/20 0.47
CYP1A2 P05177 2/20 0.45
CYP3A4 P08684 2/20 0.45
CYP2C9 P11712 2/20 0.45
CYP2C19 P33261 2/20 0.45
LMNA P02545 1/20 0.45
PGR P06401 1/20 0.45
CHRM2 P08172 1/20 0.45
ADORA3 P0DMS8 1/20 0.45
AR P10275 1/20 0.45
CYP2D6 P10635 1/20 0.45
MAPT P10636 1/20 0.45
CHRM1 P11229 1/20 0.45
ALOX15 P16050 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14498224 0.92 ESR1 (0.74) ESR1ESR2PDCD1CD274MIF
SCHEMBL144607 0.90 ESR1 (0.71) ESR1ESR2PDCD1CD274MIF
SCHEMBL547164 0.89 ESR1 (1.00) ESR1ESR2PDCD1CD274TAAR1
SCHEMBL9810145 0.89 ESR1 (1.00) ESR1ESR2PDCD1CD274TAAR1
SCHEMBL296781 0.89 ESR1 (1.00) ESR1ESR2PDCD1CD274TAAR1
SCHEMBL1171038 0.89 ESR1 (1.00) ESR1ESR2PDCD1CD274TAAR1
Ammonia Solution, Strong SCHEMBL5329244 0.87 ESR1 (0.96) ESR1ESR2PDCD1CD274TAAR1
SCHEMBL4649854 0.87 ESR1 (0.67) ESR1ESR2PDCD1CD274MIF
SCHEMBL21855360 0.85 ESR1 (0.65) ESR1ESR2PDCD1CD274MIF
SCHEMBL4905759 0.83 ESR1 (0.88) ESR1ESR2PDCD1CD274TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110008579-A1 MULTI-WALL SHEET WITHOUT THE TRIANGLE EFFECT, COATED BY COEXTRUSION BAYER MATERIALSCIENCE AG (DE) 2011-01-13 US disclosed
US-7824589-B2 Multi-wall sheet without the triangle effect, coated by coextrusion BAYER POLYMERS SHEET EUROPE GMBH (DE) 2010-11-02 US disclosed
EP-1792703-B1 Multi-layer board coated by co-extrusion without triangle effect BAYER SHEET EUROP GMBH (DE) 2010-07-14 EP disclosed
EP-1792703-A2 Multi-layer board coated by co-extrusion without triangle effect Bayer Sheet Europe GmbH (DE) 2007-06-06 EP disclosed
EP-1625006-B1 PROCESS FOR MANUFACTURING A MULTILAYERED PLATE WITHOUT ANY TRIANGLE EFFECT COATED BY COEXTRUSION BAYER SHEET EUROP GMBH (DE) 2007-03-07 EP disclosed
US-7186766-B2 Polyacetal resin composition and process for producing the same POLYPLASTICS CO., LTD. (JP) 2007-03-06 US disclosed
US-20040229062-A1 Multi-wall sheet without the triangle effect, coated by coextrusion BAYER POLMERS SHEET EUROPE GMBH (DE) 2004-11-18 US disclosed
US-6753363-B1 BASIC NITROGEN-CONTAINING COMPOUND, PHOSPHORUS COMPOUND FLAME RETARDANT, AND AROMATIC COMPOUND ACCELERATOR; MOLDABILITY POLYPLASTICS CO., LTD. (JP) 2004-06-22 US disclosed
US-20040010064-A1 Polyacetal resin composition and process for producing the same POLYPLASTICS CO., LTD. (JP) 2004-01-15 US disclosed