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SCHEMBL14460792

SCHEMBL14460792

COCOc1c(-c2ccccc2O[C@@H](C)C[C@H](C)Oc2ccccc2-c2cc(C)cc(-c3c4c(cc5c3CCCC5)CCCC4)c2OCOC)cc(C)cc1-c1c2c(cc3c1CCCC3)CCCC2

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ DRD2 P14416 1/20 0.31
▸ DRD1 P21728 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14460838 1.00 DRD2 (0.31) DRD2DRD1MEN1KMT2A
SCHEMBL14460803 0.88 GAA (0.32) —
SCHEMBL14476829 0.88 GAA (0.32) —
SCHEMBL14460812 0.88 PPARG (0.31) —
SCHEMBL17677451 0.85 — —
SCHEMBL14460783 0.83 MEN1 (0.41) MEN1KMT2A
SCHEMBL14460290 0.83 MEN1 (0.41) MEN1KMT2A
SCHEMBL14460827 0.83 MEN1 (0.41) MEN1KMT2A
SCHEMBL14460233 0.83 MEN1 (0.41) MEN1KMT2A
SCHEMBL14460821 0.83 MEN1 (0.31) DRD2DRD1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1751169-B1 BRIDGED BI-AROMATIC CATALYSTS, COMPLEXES, AND METHOD OF USING THE SAME SYMYX SOLUTIONS INC (US) 2016-04-13 — — EP disclosed
US-7241714-B2 Bridged bi-aromatic catalysts, complexes, and methods of using the same SYMYX TECHNOLOGIES, INC. (US) 2007-07-10 — — US disclosed
US-7241714-B2 Bridged bi-aromatic catalysts, complexes, and methods of using the same SYMYX TECHNOLOGIES, INC. (US) 2007-07-10 — — US disclosed