SCHEMBL1446225

SCHEMBL1446225

CCOC(=O)[C@H](CCCCN)N(N=C=O)N=C=O

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 4/20 0.47
CYP1A2 P05177 1/20 0.38
EPOR P19235 2/20 0.33
GSR P00390 1/20 0.32
RNPEP Q9H4A4 1/20 0.31
GNAI3 P08754 1/20 0.30
GNAO1 P09471 1/20 0.30
GNAI1 P63096 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1446701 1.00 CPB2 (0.47) CPB2CYP1A2EPORGSRRNPEP
SCHEMBL495076 0.87 EPOR (0.44) CPB2EPORGSRRNPEPGNAI3
SCHEMBL20261995 0.80 GSR (0.44) CPB2EPORGSRRNPEP
SCHEMBL5079013 0.80 GSR (0.44) CPB2EPORGSRRNPEP
SCHEMBL132632 0.77 GSR (0.34) CPB2GSRRNPEP
SCHEMBL17102907 0.70 CPB2 (0.61) CPB2CYP1A2GSRRNPEPGNAI3
SCHEMBL515442 0.70 GSR (0.31) CPB2GSRRNPEP
SCHEMBL25176286 0.69 CPB2 (0.51) CPB2CYP1A2GSRRNPEPGNAI3
SCHEMBL29233124 0.69 CPB2 (0.51) CPB2CYP1A2GSRRNPEPGNAI3
SCHEMBL1390932 0.69 CPB2 (0.51) CPB2CYP1A2GSRRNPEPGNAI3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2301597-A1 Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom United States Surgical Corporation (US) 2011-03-30 EP claimed
EP-2036582-A1 Biobsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom United States Surgical Corporation (US) 2009-03-18 EP claimed
EP-0693294-B1 Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom UNITED STATES SURGICAL CORP (US) 2008-10-15 EP claimed
US-7097907-B2 Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom UNITED STATES SURGICAL CORPORATION (US) 2006-08-29 US claimed
US-20060014023-A9 BIOABSORBABLE BRANCHED POLYMERS CONTAINING UNITS DERIVED FROM DIOXANONE AND MEDICAL/SURGICAL DEVICES MANUFACTURED THEREFROM COVIDIEN LP 2006-01-19 US claimed
US-20040058164-A1 Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom BENNETT STEVEN L (US) 2004-03-25 US claimed
US-6207767-B1 PROVIDING A POLYLACTONE STAR POLYMER, ENDCAPPING THE POLYMER WITH LYSINE DIISOCYANATE, CROSSLINKING THE ENDCAPPED POLYMER BY CONTACTING IT WITH A COMPOUND SELECTED FROM WATER, DIETHYLENE GLYCOL AND POLYETHYLENE GLYCOL UNITED STATES SURGICAL CORPORATION 2001-03-27 US claimed
US-5578662-A ENDCAPPED WITH LYSINE ISOCYANATE GROUPS; PROMOTES WOUND HEALING UNITED STATES SURGICAL CORPORATION (US) 1996-11-26 US claimed
EP-0693294-A2 Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom United States Surgical Corporation (US) 1996-01-24 EP claimed
EP-2462939-A2 Bioabsorbable adhesive compounds and compositions Tyco Healthcare Group LP (US) 2012-06-13 EP disclosed
EP-2301597-A1 Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom United States Surgical Corporation (US) 2011-03-30 EP disclosed
US-7759431-B2 Joining tissue with bioabsorbable isocyanate TYCO HEALTHCARE GROUP LP (US) 2010-07-20 US disclosed
US-20100145369-A1 BIOABSORBABLE ADHESIVE COMPOUNDS AND COMPOSITIONS TYCO HEALTHCARE GROUP LP (US) 2010-06-10 US disclosed
US-7691949-B2 Joining tissues with composition of bioabsorbable isocyanate and amine-substituted polyalkylene glycol TYCO HEALTHCARE GROUP LP (US) 2010-04-06 US disclosed
US-20020032298-A1 Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom BENNETT STEVEN L (US) 2002-03-14 US disclosed
US-6339130-B1 USEFUL, AS FIBER COATINGS, SURGICAL ADHESIVES OR BONE PUTTY, OR TISSUE GROWTH SUBSTRATE UNITED STATES SURGICAL CORPORATION 2002-01-15 US disclosed
US-6207767-B1 PROVIDING A POLYLACTONE STAR POLYMER, ENDCAPPING THE POLYMER WITH LYSINE DIISOCYANATE, CROSSLINKING THE ENDCAPPED POLYMER BY CONTACTING IT WITH A COMPOUND SELECTED FROM WATER, DIETHYLENE GLYCOL AND POLYETHYLENE GLYCOL UNITED STATES SURGICAL CORPORATION 2001-03-27 US disclosed
EP-0837084-A2 Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom United States Surgical Corporation (US) 1998-04-22 EP disclosed
US-5578662-A ENDCAPPED WITH LYSINE ISOCYANATE GROUPS; PROMOTES WOUND HEALING UNITED STATES SURGICAL CORPORATION (US) 1996-11-26 US disclosed
EP-0693294-A2 Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom United States Surgical Corporation (US) 1996-01-24 EP disclosed