SCHEMBL14463277

SCHEMBL14463277

CCCCN1COc2ccccc2C1

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.54
CYP1A2 P05177 1/20 0.54
CYP2D6 P10635 1/20 0.54
CYP2C19 P33261 1/20 0.54
SIGMAR1 Q99720 10/20 0.43
EBP Q15125 1/20 0.40
APP P05067 1/20 0.39
CHRM2 P08172 1/20 0.39
CHRM4 P08173 1/20 0.39
CHRM5 P08912 1/20 0.39
CHRM1 P11229 1/20 0.39
DRD2 P14416 1/20 0.39
CHRM3 P20309 1/20 0.39
DRD4 P21917 1/20 0.39
DRD3 P35462 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2577142 0.95 ALDH1A1 (0.61) ALDH1A1CYP1A2CYP2D6CYP2C19SIGMAR1
SCHEMBL28344188 0.94 ALDH1A1 (0.64) ALDH1A1CYP1A2CYP2D6CYP2C19SIGMAR1
SCHEMBL24419882 0.90 CYP1A2 (0.45) ALDH1A1CYP1A2CYP2D6CYP2C19SIGMAR1
SCHEMBL13224414 0.86 CYP1A2 (0.40) ALDH1A1CYP1A2CYP2D6CYP2C19SIGMAR1
SCHEMBL29356128 0.86 CYP1A2 (0.40) ALDH1A1CYP1A2CYP2D6CYP2C19SIGMAR1
SCHEMBL111045 0.84 APP (0.42) ALDH1A1CYP1A2CYP2D6CYP2C19SIGMAR1
SCHEMBL28344198 0.83 ALDH1A1 (0.48) ALDH1A1CYP1A2CYP2D6CYP2C19SIGMAR1
SCHEMBL8034574 0.83 CYP1A2 (0.40) ALDH1A1CYP1A2CYP2D6CYP2C19APP
SCHEMBL2596955 0.81 CYP1A2 (0.40) ALDH1A1CYP1A2CYP2D6CYP2C19APP
SCHEMBL12522699 0.81 CYP2D6 (0.41) ALDH1A1CYP1A2CYP2D6CYP2C19SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1621566-B1 Fluxing no-flow underfill composition containing benzoxazines NAT STARCH CHEM INVEST (US) 2007-07-04 EP disclosed