Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 11/20 | 0.64 |
| ▸ | BAD | Q92934 | 4/20 | 0.63 |
| ▸ | BCL2L1 | Q07817 | 13/20 | 0.62 |
| ▸ | BCL2L2 | Q92843 | 3/20 | 0.62 |
| ▸ | BCL2L11 | O43521 | 2/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.62 |
| ▸ | ASPH | Q12797 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | MDM4 | O15151 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | BID | P55957 | 1/20 | 0.58 |
| ▸ | BAX | Q07812 | 1/20 | 0.58 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.58 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.58 |
| ▸ | BBC3 | Q9BXH1 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7872304 | 0.95 | BCL2L1 (0.67) | BCL2BADBCL2L1BCL2L2BCL2L11 | |
| SCHEMBL12574586 | 0.94 | BCL2 (0.63) | BCL2BADBCL2L1BCL2L2BCL2L11 | |
| SCHEMBL15417701 | 0.93 | BCL2 (0.63) | BCL2BADBCL2L1BCL2L2BCL2L11 | |
| SCHEMBL19424240 | 0.92 | BCL2 (0.72) | BCL2BADBCL2L1BCL2L2BCL2L11 | |
| SCHEMBL19425083 | 0.92 | BCL2 (0.73) | BCL2BADBCL2L1BCL2L2BCL2L11 | |
| SCHEMBL19424355 | 0.92 | BCL2 (0.74) | BCL2BADBCL2L1BCL2L2BCL2L11 | |
| SCHEMBL19424302 | 0.91 | BCL2 (0.61) | BCL2BADBCL2L1BCL2L2BCL2L11 | |
| SCHEMBL19425078 | 0.89 | BCL2L1 (0.68) | BCL2BADBCL2L1 | |
| SCHEMBL19424257 | 0.89 | BCL2L1 (0.76) | BCL2BADBCL2L1BCL2L2BCL2L11 | |
| SCHEMBL19425006 | 0.88 | BCL2L1 (0.62) | BCL2BADBCL2L1BCL2L2BCL2L11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007040650-A9 | APOPTOSIS PROMOTERS | ABBOTT LAB (US) | 2007-07-26 | — | — | WO | disclosed |
| WO-2007040650-A2 | APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2007-04-12 | — | — | WO | disclosed |