Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RGS12 | O14924 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23173777 | 0.76 | PRKACA (0.54) | MEN1KMT2APARP1NPSR1USP2 | |
| SCHEMBL2188830 | 0.74 | CYP11B1 (0.48) | MEN1KMT2APOLBCYP1A2MAPT | |
| SCHEMBL24179211 | 0.72 | ALDH1A1 (0.36) | MEN1KMT2APOLBCYP1A2CASP1 | |
| SCHEMBL25839484 | 0.71 | POLB (0.51) | POLBMAPTKEAP1NFE2L2SMN1; SMN2 | |
| SCHEMBL28465394 | 0.70 | MEN1 (0.56) | MEN1KMT2APARP1NPSR1USP2 | |
| SCHEMBL28411756 | 0.69 | MEN1 (0.54) | MEN1KMT2APARP1NPSR1USP2 | |
| SCHEMBL14463520 | 0.69 | MEN1 (0.57) | MEN1KMT2APARP1NPSR1USP2 | |
| SCHEMBL19968134 | 0.68 | CYP17A1 (0.57) | MEN1KMT2ACYP1A2MGAMGAA | |
| SCHEMBL3421714 | 0.68 | MEN1 (0.59) | MEN1KMT2APARP1NPSR1USP2 | |
| SCHEMBL14463495 | 0.67 | CYP3A4 (0.48) | MEN1KMT2APARP1NPSR1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007064345-A9 | HETEROCYCLIC-SUBSTITUTED BIS-1,8 NAPHTHALIMIDE COMPOUNDS, ANTIBODY DRUG CONJUGATES, AND METHODS OF USE | GENENTECH INC (US) | 2007-07-12 | — | — | WO | disclosed |