Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.74 |
| ▸ | LMNA | P02545 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 6/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | CSF1R | P07333 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GRM6 | O15303 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14463975 | 0.94 | SMN1; SMN2 (0.66) | SMN1; SMN2LMNAMEN1KMT2AMAPT | |
| SCHEMBL10474547 | 0.92 | SMN1; SMN2 (0.63) | SMN1; SMN2LMNAMEN1KMT2AMAPT | |
| SCHEMBL14463978 | 0.90 | SMN1; SMN2 (0.60) | SMN1; SMN2LMNAMEN1KMT2AMAPT | |
| SCHEMBL14916920 | 0.88 | FABP4 (0.62) | SMN1; SMN2LMNAMEN1KMT2AMAPT | |
| SCHEMBL31442528 | 0.86 | SMN1; SMN2 (0.97) | SMN1; SMN2LMNAMEN1KMT2AMAPT | |
| SCHEMBL5505353 | 0.86 | SMN1; SMN2 (0.97) | SMN1; SMN2LMNAMEN1KMT2AMAPT | |
| SCHEMBL1063212 | 0.85 | KDM4E (0.59) | SMN1; SMN2LMNAMEN1KMT2AMAPT | |
| SCHEMBL29799068 | 0.85 | KDM4E (0.59) | SMN1; SMN2LMNAMEN1KMT2AMAPT | |
| SCHEMBL7248226 | 0.85 | KDM4E (0.70) | SMN1; SMN2LMNAMEN1KMT2AMAPT | |
| SCHEMBL27327783 | 0.84 | KDM4E (0.57) | SMN1; SMN2LMNAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007074491-A1 | HETEROTRICYCLIC AMIDE DERIVATIVES AS NEUROKININ-l (NKl) RECEPTOR LIGANDS | UNIVERSITA DEGLI STUDI DI SIENA (IT) | 2007-07-05 | — | — | WO | disclosed |