Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12763942 | 0.93 | PROKR1 (0.49) | PROKR1P2RX3 | |
| SCHEMBL12158769 | 0.89 | PROKR1 (0.43) | PROKR1P2RX3 | |
| SCHEMBL17278166 | 0.87 | PROKR1 (0.48) | PROKR1P2RX3 | |
| SCHEMBL12763941 | 0.87 | PROKR1 (0.47) | PROKR1P2RX3 | |
| SCHEMBL10254919 | 0.87 | PROKR1 (0.48) | PROKR1P2RX3 | |
| SCHEMBL10254917 | 0.83 | PROKR1 (0.44) | PROKR1P2RX3 | |
| SCHEMBL10254892 | 0.82 | P2RX3 (0.46) | PROKR1P2RX3 | |
| SCHEMBL10254561 | 0.81 | P2RX3 (0.46) | PROKR1P2RX3 | |
| SCHEMBL14715688 | 0.81 | PROKR1 (0.47) | PROKR1P2RX3 | |
| SCHEMBL10254303 | 0.79 | P2RX3 (0.46) | PROKR1P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079214-A2 | PROKINETICIN 2 RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-12 | — | — | WO | disclosed |