Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTP4A3 | O75365 | 6/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NAT1 | P18440 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CISD1 | Q9NZ45 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 2/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10090318 | 0.87 | PTP4A3 (0.53) | PTP4A3POLBMAPTMEN1NPC1 | |
| SCHEMBL10090316 | 0.79 | PTP4A3 (0.61) | PTP4A3MEN1KMT2ANAT1GSK3B | |
| SCHEMBL2067673 | 0.79 | PTP4A3 (0.61) | PTP4A3MEN1KMT2ANAT1GSK3B | |
| SCHEMBL2066148 | 0.78 | PTP4A3 (0.51) | PTP4A3POLBMAPTMEN1NPC1 | |
| SCHEMBL10090317 | 0.78 | PTP4A3 (0.51) | PTP4A3POLBMAPTMEN1NPC1 | |
| SCHEMBL12892067 | 0.74 | PTP4A3 (0.65) | PTP4A3POLBMAPTMEN1NPC1 | |
| SCHEMBL10090186 | 0.73 | PTP4A3 (0.57) | PTP4A3MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL2065103 | 0.73 | PTP4A3 (0.57) | PTP4A3MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL14464062 | 0.70 | PTP4A3 (0.64) | PTP4A3POLBMAPTMEN1KMT2A | |
| SCHEMBL2065355 | 0.70 | PTP4A3 (0.61) | PTP4A3GSK3BCISD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007081091-A1 | RHODANDSE DERIVARIVES, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2007-07-19 | — | — | WO | disclosed |