Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTP4A3 | O75365 | 6/20 | 0.65 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.56 |
| ▸ | NAT1 | P18440 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | MYC | P01106 | 1/20 | 0.49 |
| ▸ | MAX | P61244 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14529265 | 0.86 | NAT1 (0.59) | PTP4A3NAT1MEN1MAPTKMT2A | |
| SCHEMBL14463961 | 0.84 | PTP4A3 (0.64) | PTP4A3CISD1NAT1NPC1RAB9A | |
| SCHEMBL10090318 | 0.82 | PTP4A3 (0.53) | PTP4A3CISD1NAT1MEN1MAPT | |
| SCHEMBL14464046 | 0.82 | PTP4A3 (0.71) | PTP4A3CISD1NAT1MEN1MAPT | |
| SCHEMBL13499558 | 0.79 | PTP4A3 (0.71) | PTP4A3CISD1NAT1MYCMAX | |
| SCHEMBL14464056 | 0.79 | PTP4A3 (1.00) | PTP4A3CISD1NAT1MYCMAX | |
| SCHEMBL14463959 | 0.79 | PTP4A3 (0.71) | PTP4A3CISD1NAT1MEN1MAPT | |
| SCHEMBL10090151 | 0.77 | PTP4A3 (0.69) | PTP4A3CISD1NAT1MEN1MAPT | |
| SCHEMBL13499559 | 0.76 | PTP4A3 (0.67) | PTP4A3CISD1NAT1MYCMAX | |
| SCHEMBL2066304 | 0.76 | PTP4A3 (0.68) | PTP4A3CISD1NAT1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7879893-B2 | Zinc binding ligand; sustained release of insulin | NOVO NORDISK A/S (DK) | 2011-02-01 | — | — | US | disclosed |
| US-7879893-B2 | Zinc binding ligand; sustained release of insulin | NOVO NORDISK A/S (DK) | 2011-02-01 | — | — | US | disclosed |
| EP-1585541-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING INSULIN AND LEGENDS OF INSULIN HEXAMER | NOVO NORDISK AS (DK) | 2007-11-14 | — | — | EP | disclosed |