Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 19/20 | 0.72 |
| ▸ | PTGER2 | P43116 | 10/20 | 0.72 |
| ▸ | PTGER3 | P43115 | 9/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11830503 | 0.84 | PTGER4 (1.00) | PTGER4PTGER2PTGER3 | |
| SCHEMBL11830499 | 0.84 | PTGER4 (1.00) | PTGER4PTGER2PTGER3 | |
| SCHEMBL14268646 | 0.83 | PTGER4 (0.76) | PTGER4PTGER2PTGER3 | |
| SCHEMBL11660455 | 0.82 | PTGER4 (0.81) | PTGER4PTGER2PTGER3KCNH2 | |
| SCHEMBL5217323 | 0.82 | PTGER4 (0.90) | PTGER4PTGER2PTGER3 | |
| SCHEMBL11664455 | 0.82 | PTGER4 (0.79) | PTGER4PTGER2PTGER3KCNH2 | |
| SCHEMBL5217330 | 0.82 | PTGER4 (0.90) | PTGER4PTGER2PTGER3 | |
| SCHEMBL5214140 | 0.82 | PTGER4 (0.90) | PTGER4PTGER2PTGER3 | |
| SCHEMBL6612898 | 0.81 | PTGER4 (0.64) | PTGER4PTGER2PTGER3 | |
| SCHEMBL6612900 | 0.81 | PTGER4 (0.64) | PTGER4PTGER2PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408961-B1 | 2 PYRROLIDONE DERIVATIVES AS PROSTANOID AGONISTS | HOFFMANN LA ROCHE (CH) | 2007-07-11 | — | — | EP | disclosed |