Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.73 |
| ▸ | MEN1 | O00255 | 6/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.73 |
| ▸ | GRK6 | P43250 | 1/20 | 0.71 |
| ▸ | AR | P10275 | 2/20 | 0.63 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.62 |
| ▸ | MASP2 | O00187 | 1/20 | 0.61 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.61 |
| ▸ | CD44 | P16070 | 1/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.61 |
| ▸ | MSN | P26038 | 1/20 | 0.61 |
| ▸ | CDC25B | P30305 | 1/20 | 0.61 |
| ▸ | AKT1 | P31749 | 1/20 | 0.61 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.61 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 5/20 | 0.61 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.61 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.61 |
| ▸ | CASP3 | P42574 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL681674 | 0.88 | MAPT (0.81) | MAPTMEN1KMT2AKDM4EGRK6 | |
| SCHEMBL23949811 | 0.88 | MAPT (0.81) | MAPTMEN1KMT2AKDM4EGRK6 | |
| SCHEMBL23949812 | 0.87 | MAPT (0.76) | MAPTMEN1KMT2AKDM4EGRK6 | |
| SCHEMBL17458830 | 0.87 | MAPT (0.76) | MAPTMEN1KMT2AKDM4EGRK6 | |
| SCHEMBL17464587 | 0.87 | MAPT (0.76) | MAPTMEN1KMT2AKDM4EGRK6 | |
| SCHEMBL23950052 | 0.87 | MAPT (0.76) | MAPTMEN1KMT2AKDM4EGRK6 | |
| SCHEMBL23949489 | 0.87 | MAPT (0.76) | MAPTMEN1KMT2AKDM4EGRK6 | |
| SCHEMBL686171 | 0.86 | AR (0.84) | MAPTMEN1KMT2AKDM4EGRK6 | |
| SCHEMBL23949937 | 0.85 | MEN1 (0.73) | MAPTMEN1KMT2AKDM4EGRK6 | |
| SCHEMBL15300006 | 0.84 | GRK6 (0.78) | MAPTMEN1KMT2AKDM4EGRK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007048042-A9 | SMALL MOLECULE INHIBITORS OF HIV-1 CAPSID ASSEMBLY | UNIV ALABAMA (US) | 2007-07-05 | — | — | WO | disclosed |