Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | MAOB | P27338 | 5/20 | 0.67 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NT5E | P21589 | 1/20 | 0.49 |
| ▸ | F12 | P00748 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1366856 | 0.91 | KDM4E (0.79) | KDM4EMAOBGPR35ALDH1A1CYP1A2 | |
| SCHEMBL13857104 | 0.84 | MAOB (0.68) | KDM4EMAOBGPR35ALDH1A1CYP1A2 | |
| SCHEMBL14464476 | 0.84 | MAOB (0.68) | KDM4EMAOBGPR35ALDH1A1CYP1A2 | |
| SCHEMBL14464475 | 0.83 | KDM4E (0.67) | KDM4EMAOBGPR35ALDH1A1CYP1A2 | |
| SCHEMBL13857249 | 0.83 | MAOB (0.69) | KDM4EMAOBGPR35ALDH1A1CYP1A2 | |
| SCHEMBL1368563 | 0.82 | KDM4E (0.79) | KDM4EMAOBGPR35ALDH1A1CYP1A2 | |
| SCHEMBL9068782 | 0.80 | KDM4E (1.00) | KDM4EMAOBGPR35ALDH1A1CYP1A2 | |
| SCHEMBL52086 | 0.80 | MAOB (0.72) | KDM4EMAOBGPR35ALDH1A1CYP1A2 | |
| SCHEMBL14464474 | 0.80 | KMT2A (0.73) | KDM4EMAOBGPR35ALDH1A1CYP1A2 | |
| SCHEMBL17037285 | 0.79 | MAOB (1.00) | KDM4EMAOBGPR35ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007082178-A2 | PROSTAGLANDIN REDUCTASE INHIBITORS | ABGENOMICS CORPORATION (TW) | 2007-07-19 | — | — | WO | disclosed |