Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | CA1 | P00915 | 2/20 | 0.69 |
| ▸ | CA2 | P00918 | 2/20 | 0.69 |
| ▸ | CA12 | O43570 | 1/20 | 0.69 |
| ▸ | CA3 | P07451 | 1/20 | 0.69 |
| ▸ | CA6 | P23280 | 1/20 | 0.69 |
| ▸ | CA5A | P35218 | 1/20 | 0.69 |
| ▸ | CA7 | P43166 | 1/20 | 0.69 |
| ▸ | CA9 | Q16790 | 1/20 | 0.69 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.69 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.69 |
| ▸ | MAOB | P27338 | 9/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2032914 | 0.92 | KDM4E (0.81) | KMT2AKDM4EALDH1A1HPGDCA1 | |
| SCHEMBL1366856 | 0.87 | KDM4E (0.79) | KMT2AMEN1KDM4EALDH1A1CA1 | |
| SCHEMBL13857249 | 0.82 | MAOB (0.69) | KMT2AMEN1KDM4EALDH1A1CA1 | |
| SCHEMBL4346175 | 0.82 | MEN1 (0.67) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL1366464 | 0.82 | MEN1 (0.67) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL1366462 | 0.82 | MEN1 (0.67) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL978456 | 0.82 | KDM4E (1.00) | KMT2AKDM4EALDH1A1HPGDCA1 | |
| SCHEMBL29963204 | 0.82 | KDM4E (1.00) | KMT2AKDM4EALDH1A1HPGDCA1 | |
| SCHEMBL7527810 | 0.82 | ALDH1A1 (1.00) | KMT2AKDM4EALDH1A1HPGDCA1 | |
| SCHEMBL1366572 | 0.82 | KMT2A (0.69) | KMT2AMEN1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007082178-A2 | PROSTAGLANDIN REDUCTASE INHIBITORS | ABGENOMICS CORPORATION (TW) | 2007-07-19 | — | — | WO | disclosed |