Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 8/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3952963 | 0.83 | MAPK1 (0.51) | ALDH1A1HSD17B10ALOX15HPGDSMN1; SMN2 | |
| SCHEMBL3720200 | 0.79 | ESR1 (0.48) | ALDH1A1HSD17B10ALOX15HPGDALOX12 | |
| SCHEMBL10888353 | 0.79 | MEN1 (0.38) | ALDH1A1HSD17B10ALOX15HPGDALOX12 | |
| SCHEMBL3784454 | 0.79 | SLC6A4 (0.37) | ALDH1A1MAPTMCL1SLC6A4MAOA | |
| SCHEMBL3723662 | 0.78 | HSD17B10 (0.50) | ALDH1A1HSD17B10ALOX15HPGDALOX12 | |
| SCHEMBL11777073 | 0.78 | SLC6A4 (0.39) | ALDH1A1MAPTSLC6A4MAOAGCK | |
| SCHEMBL3786473 | 0.78 | TSHR (0.50) | ALDH1A1HSD17B10ALOX15HPGDALOX12 | |
| SCHEMBL4544572 | 0.76 | ALDH1A1 (0.54) | ALDH1A1HSD17B10ALOX15HPGDALOX12 | |
| SCHEMBL9361517 | 0.75 | SLC6A4 (0.40) | ALDH1A1HSD17B10ALOX15GAAPKM | |
| SCHEMBL27229140 | 0.75 | ALDH1A1 (0.46) | ALDH1A1HSD17B10ALOX15MAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2302000-A1 | Curable composition and catalyst composition | KANEKA CORPORATION (JP) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009021750-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2009-02-19 | — | — | WO | disclosed |
| WO-2009021750-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2009-02-19 | — | — | WO | disclosed |