Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 8/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD4 | P21917 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14443111 | 0.92 | SRD5A1 (0.50) | SRD5A1CNR1DRD2DRD4ALDH1A1 | |
| SCHEMBL14443190 | 0.68 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL14596436 | 0.68 | CNR1 (0.58) | CNR1LMNA | |
| SCHEMBL11980424 | 0.66 | HTR2C (0.49) | CNR1ALDH1A1 | |
| SCHEMBL14464872 | 0.66 | CNR1 (0.40) | CNR1DRD2DRD4ALDH1A1 | |
| SCHEMBL11958220 | 0.66 | HTR2C (0.49) | CNR1ALDH1A1 | |
| SCHEMBL11958239 | 0.65 | DPP4 (0.49) | LMNAPOLBALDH1A1 | |
| SCHEMBL11958853 | 0.65 | MDM2 (0.52) | LMNAPOLBALDH1A1 | |
| SCHEMBL14787423 | 0.65 | CNR1 (0.49) | CNR1DRD2DRD4LMNAPOLB | |
| SCHEMBL4711423 | 0.64 | CNR1 (0.52) | CNR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007084319-A2 | DIARYL PIPERIDINES AS CB1 MODULATORS | SCHERING CORPORATION (US) | 2007-07-26 | — | — | WO | disclosed |