Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 5/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13500264 | 0.73 | CDK8 (0.47) | GAAMAPTALDH1A1KMT2ARAB9A | |
| SCHEMBL14433948 | 0.72 | MEN1 (0.69) | S1PR2TP53LMNAGAAMAPT | |
| SCHEMBL18415480 | 0.71 | ALDH1A1 (0.51) | MAPTALDH1A1HPGDKMT2A | |
| SCHEMBL3585164 | 0.71 | LCK (0.46) | MAPK1TP53MAPTALDH1A1RAB9A | |
| SCHEMBL9598851 | 0.71 | S1PR2 (0.65) | S1PR2MAPTALDH1A1KMT2ARAB9A | |
| SCHEMBL22125334 | 0.71 | S1PR2 (1.00) | S1PR2LMNAMAPTALDH1A1NPSR1 | |
| SCHEMBL13190872 | 0.71 | EPHX2 (0.48) | LMNAMAPTALDH1A1HPGDKMT2A | |
| SCHEMBL33528965 | 0.70 | ALDH1A1 (0.50) | MAPTALDH1A1HPGDKMT2A | |
| SCHEMBL14433835 | 0.70 | ALDH1A1 (0.54) | MAPK1LMNAGAAMAPTALDH1A1 | |
| SCHEMBL17593381 | 0.70 | ALDH1A1 (0.39) | GAAMAPTALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076055-A2 | COMPOSITIONS AND METHODS COMPRISING PROTEINASE ACTIVATED RECEPTOR ANTAGONISTS | ENTREMED, INC. (US) | 2007-07-05 | — | — | WO | disclosed |