Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5022935 | 0.85 | MAPT (0.68) | MAPTRAB9ANPC1MAPK1NFKB1 | |
| SCHEMBL23927084 | 0.84 | MAPT (0.60) | MAPTRAB9ANPC1MAPK1NFKB1 | |
| SCHEMBL30079650 | 0.84 | MAPT (0.60) | MAPTRAB9ANPC1MAPK1NFKB1 | |
| SCHEMBL29241859 | 0.82 | MAPT (0.68) | MAPTRAB9ANPC1MAPK1NFKB1 | |
| SCHEMBL6791419 | 0.82 | MAPT (0.60) | MAPTRAB9ANPC1MAPK1NFKB1 | |
| SCHEMBL6347219 | 0.81 | MEN1 (0.62) | MAPTRAB9ANPC1MAPK1NFKB1 | |
| SCHEMBL15954978 | 0.81 | MAPT (0.56) | MAPTRAB9ANPC1MAPK1NFKB1 | |
| SCHEMBL29580711 | 0.81 | MAPT (0.56) | MAPTRAB9ANPC1MAPK1NFKB1 | |
| SCHEMBL29180302 | 0.81 | MAPT (0.59) | MAPTRAB9ANPC1MAPK1NFKB1 | |
| SCHEMBL2177925 | 0.80 | MAPT (0.69) | MAPTRAB9ANPC1MAPK1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075629-A2 | PHENOXYPIPERIDINES AND ANALOGS THEREOF USEFUL AS HISTAMINE H3 ANTAGONISTS | SCHERING CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |