Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 18/20 | 0.57 |
| ▸ | NR1H3 | Q13133 | 18/20 | 0.57 |
| ▸ | PPARD | Q03181 | 13/20 | 0.57 |
| ▸ | PPARA | Q07869 | 12/20 | 0.57 |
| ▸ | PPARG | P37231 | 9/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14465279 | 0.91 | NR1H2 (0.58) | NR1H2NR1H3PPARDPPARAPPARG | |
| SCHEMBL14466216 | 0.89 | NR1H2 (0.57) | NR1H2NR1H3PPARDPPARAPPARG | |
| SCHEMBL14465356 | 0.84 | NR1H2 (0.62) | NR1H2NR1H3PPARDPPARAPPARG | |
| SCHEMBL7040305 | 0.83 | NR1H3 (0.81) | NR1H2NR1H3PPARDPPARAPPARG | |
| SCHEMBL14465344 | 0.83 | NR1H3 (0.72) | NR1H2NR1H3PPARDPPARAPPARG | |
| SCHEMBL8006436 | 0.83 | NR1H3 (0.69) | NR1H2NR1H3PPARDPPARAPPARG | |
| SCHEMBL14465318 | 0.80 | NR1H2 (0.63) | NR1H2NR1H3PPARDPPARAPPARG | |
| SCHEMBL6346185 | 0.78 | NR1H3 (0.67) | NR1H2NR1H3PPARDPPARAPPARG | |
| SCHEMBL6349285 | 0.78 | NR1H3 (0.67) | NR1H2NR1H3PPARDPPARAPPARG | |
| SCHEMBL6099414 | 0.77 | NR1H3 (0.69) | NR1H2NR1H3PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007081335-A1 | THERAPEUTIC COMPOUNDS FOR TREATING DYSLIPIDEMIC CONDITIONS | MERCK & CO., INC. (US) | 2007-07-19 | — | — | WO | disclosed |