Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.83 |
| ▸ | PPARA | Q07869 | 11/20 | 0.83 |
| ▸ | PPARD | Q03181 | 11/20 | 0.83 |
| ▸ | NR1H2 | P55055 | 7/20 | 0.83 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14465320 | 0.94 | PPARG (0.83) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL5943621 | 0.91 | PPARG (1.00) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL5008698 | 0.90 | PPARA (1.00) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL14465583 | 0.90 | PPARG (0.77) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL14465317 | 0.89 | PPARG (0.77) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL14465301 | 0.88 | PPARG (0.86) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL5336258 | 0.86 | PPARA (1.00) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL14465571 | 0.86 | PPARA (0.75) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL14465561 | 0.85 | PPARA (0.76) | PPARGPPARAPPARDNR1H2NR1H3 | |
| SCHEMBL5012506 | 0.84 | PPARG (0.83) | PPARGPPARAPPARDNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007081335-A1 | THERAPEUTIC COMPOUNDS FOR TREATING DYSLIPIDEMIC CONDITIONS | MERCK & CO., INC. (US) | 2007-07-19 | — | — | WO | disclosed |