Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOB | P04114 | 8/20 | 0.44 |
| ▸ | MTTP | P55157 | 16/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996540 | 0.82 | MTTP (0.53) | APOBMTTPSMO | |
| SCHEMBL6795426 | 0.78 | SMO (0.56) | APOBMTTPSMO | |
| SCHEMBL6793489 | 0.76 | SMO (0.62) | APOBMTTPSMO | |
| SCHEMBL6648279 | 0.72 | MTTP (0.60) | APOBMTTP | |
| SCHEMBL6793203 | 0.71 | TRPV1 (0.53) | APOBMTTPSMO | |
| SCHEMBL6805247 | 0.69 | MTTP (0.49) | APOBMTTPSMO | |
| SCHEMBL6794354 | 0.69 | SMO (0.61) | APOBMTTPSMO | |
| SCHEMBL6495258 | 0.69 | SMO (0.48) | APOBMTTPSMO | |
| SCHEMBL6792600 | 0.69 | KDR (0.59) | APOBMTTPSMO | |
| SCHEMBL6791178 | 0.69 | PTGS1 (0.67) | APOBMTTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1803452-A1 | ESTER DERIVATIVE AND PHARMACEUTICAL USE THEREOF | Japan Tobacco, Inc. (JP) | 2007-07-04 | — | — | EP | disclosed |