Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316583 | 1.00 | KDM4E (0.52) | KDM4ELMNAHIF1AADRA2AADRA2C | |
| SCHEMBL6319027 | 0.85 | ACACB (0.45) | KDM4ELMNAHIF1AALDH1A1RECQL | |
| SCHEMBL2034831 | 0.80 | SLC6A4 (0.53) | ALDH1A1TDP1TSHRSLC6A2SLC6A4 | |
| SCHEMBL2031199 | 0.80 | SLC6A4 (0.53) | ALDH1A1TDP1TSHRSLC6A2SLC6A4 | |
| SCHEMBL6055221 | 0.80 | ACACB (0.47) | KDM4EALDH1A1MAPTKMT2ASLC6A2 | |
| SCHEMBL2034762 | 0.80 | SLC6A4 (0.53) | ALDH1A1TDP1TSHRSLC6A2SLC6A4 | |
| SCHEMBL14465578 | 0.79 | ADRA1A (0.55) | KDM4ELMNAHIF1AADRA2AADRA2C | |
| Hydrochloric Acid SCHEMBL14157331 | 0.79 | SLC6A2 (0.51) | ALDH1A1TDP1TSHRSLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL14120624 | 0.79 | SLC6A2 (0.51) | ALDH1A1TDP1TSHRSLC6A2SLC6A4 | |
| SCHEMBL851370 | 0.79 | KDM4E (0.57) | KDM4ELMNAHIF1AADRA2AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007077140-A1 | HYDROXY-NOREPHEDRINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | BASF AKTIENGESELLSCHAFT (DE) | 2007-07-12 | — | — | WO | disclosed |