Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 17/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14465748 | 0.80 | CXCR3 (0.79) | CXCR3L3MBTL1MEN1KMT2A | |
| SCHEMBL5316605 | 0.80 | CXCR3 (0.52) | CXCR3L3MBTL1MEN1KMT2A | |
| SCHEMBL14466790 | 0.73 | CXCR3 (0.57) | CXCR3 | |
| SCHEMBL14465880 | 0.70 | CXCR3 (0.53) | CXCR3 | |
| SCHEMBL14465749 | 0.69 | CXCR3 (0.49) | CXCR3 | |
| SCHEMBL14466789 | 0.68 | CXCR3 (0.65) | CXCR3 | |
| SCHEMBL23921194 | 0.67 | CXCR3 (1.00) | CXCR3 | |
| SCHEMBL14465675 | 0.67 | CXCR3 (1.00) | CXCR3 | |
| SCHEMBL14465853 | 0.67 | CXCR3 (1.00) | CXCR3 | |
| SCHEMBL14465763 | 0.66 | CXCR3 (0.68) | CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076318-A2 | CAMPHOR-DERIVED CXCR3 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |