Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 8/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 9/20 | 0.39 |
| ▸ | MMP14 | P50281 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316606 | 0.78 | CXCR3 (0.80) | CXCR3L3MBTL1 | |
| SCHEMBL14466693 | 0.66 | CXCR3 (0.70) | CXCR3 | |
| SCHEMBL17414136 | 0.64 | CYP1A2 (0.31) | — | |
| SCHEMBL14465702 | 0.64 | — | — | |
| SCHEMBL17637714 | 0.64 | CYP1A2 (0.31) | — | |
| SCHEMBL3651006 | 0.63 | OGA (0.46) | KDM4ENPC1RAB9A | |
| SCHEMBL14238181 | 0.62 | HDAC3 (0.49) | KDM4ENPC1RAB9A | |
| SCHEMBL12503186 | 0.62 | OGA (0.47) | KDM4ENPC1RAB9A | |
| SCHEMBL12525139 | 0.62 | OGA (0.47) | KDM4ENPC1RAB9A | |
| SCHEMBL12913814 | 0.62 | HDAC3 (0.65) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076318-A2 | CAMPHOR-DERIVED CXCR3 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |