Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 20/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6005070 | 0.92 | ADAM17 (1.00) | ADAM17 | |
| SCHEMBL7906097 | 0.87 | ADAM17 (0.77) | ADAM17 | |
| SCHEMBL14466482 | 0.85 | ADAM17 (0.63) | ADAM17 | |
| SCHEMBL17570701 | 0.85 | ADAM17 (0.84) | ADAM17 | |
| SCHEMBL8227325 | 0.84 | ADAM17 (0.85) | ADAM17 | |
| SCHEMBL17570711 | 0.83 | ADAM17 (0.84) | ADAM17 | |
| SCHEMBL18699718 | 0.83 | ADAM17 (0.70) | ADAM17 | |
| SCHEMBL17570599 | 0.83 | ADAM17 (0.85) | ADAM17 | |
| SCHEMBL14467188 | 0.83 | ADAM17 (0.60) | ADAM17 | |
| SCHEMBL12860490 | 0.82 | ADAM17 (0.82) | ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007084415-A2 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2007-07-26 | — | — | WO | disclosed |