Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 3/20 | 0.40 |
| ▸ | CCR3 | P51677 | 3/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | LSS | P48449 | 1/20 | 0.38 |
| ▸ | GPR6 | P46095 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14467021 | 0.86 | EPHX2 (0.46) | EPHX2MAPK14ADRB2MLNRCYP3A4 | |
| SCHEMBL14467001 | 0.86 | ADRB2 (0.48) | EPHX2HPGDSMN1; SMN2ADRB2HSD11B1 | |
| SCHEMBL14467022 | 0.84 | EPHX2 (0.44) | EPHX2MAPK14ADRB2MLNRCYP3A4 | |
| SCHEMBL14466894 | 0.83 | EPHX2 (0.43) | EPHX2HPGDSMN1; SMN2ADRB2MLNR | |
| SCHEMBL5320414 | 0.82 | GRIN2D (0.46) | EPHX2ADRB2MLNRCYP3A4CCR3 | |
| SCHEMBL14466892 | 0.81 | GPR6 (0.51) | EPHX2HPGDSMN1; SMN2HRH1CCR3 | |
| SCHEMBL14467393 | 0.80 | EPHX2 (0.43) | EPHX2HPGDSMN1; SMN2ADRB2MLNR | |
| SCHEMBL5320384 | 0.80 | GRIN2D (0.47) | EPHX2ADRB2MLNRCYP3A4CCR3 | |
| SCHEMBL5320264 | 0.79 | GRIN2D (0.44) | EPHX2MAPK14ADRB2MLNRCYP3A4 | |
| SCHEMBL14466898 | 0.79 | GRIN2D (0.53) | EPHX2HRH1CCR3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007082079-A2 | PIPERIDINE AMIDE DERIVATIVES AS PROTEIN KINASE INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-07-19 | — | — | WO | disclosed |