Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL980952 | 0.82 | MAPT (0.53) | ESRRA | |
| SCHEMBL14468104 | 0.80 | CAPN1 (0.40) | ESRRA | |
| SCHEMBL2146801 | 0.79 | IMPDH2 (0.51) | ESRRA | |
| SCHEMBL188024 | 0.77 | KDM4E (0.54) | — | |
| SCHEMBL22778064 | 0.76 | AXL (0.40) | — | |
| SCHEMBL29714394 | 0.76 | AXL (0.40) | — | |
| SCHEMBL3055320 | 0.72 | ESRRA (0.69) | ESRRA | |
| SCHEMBL2850331 | 0.72 | IMPDH2 (0.59) | — | |
| SCHEMBL2295455 | 0.71 | — | — | |
| SCHEMBL29714400 | 0.70 | ELANE (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007084435-A2 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2007-07-26 | — | — | WO | disclosed |