SCHEMBL144679

SCHEMBL144679

CC(C)c1n[nH]c(N)c1N

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.41
PTK2B Q14289 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9358556 0.98 GAA (0.40) GAAPTK2BSMN1; SMN2
Sulfuric Acid SCHEMBL5202893 0.88 GAA (0.35) GAAPTK2BSMN1; SMN2
SCHEMBL4730394 0.83 GAA (0.33) GAAPTK2BSMN1; SMN2
SCHEMBL94061 0.81 GAA (0.32) GAAPTK2BSMN1; SMN2
SCHEMBL5252528 0.78 GAA (0.40) GAAPTK2BSMN1; SMN2
SCHEMBL21542668 0.78 GAA (0.33) GAAPTK2BSMN1; SMN2
SCHEMBL3374555 0.78 GAA (0.30) GAAPTK2BSMN1; SMN2
SCHEMBL5201388 0.72 GAA (0.36) GAAPTK2BSMN1; SMN2
SCHEMBL13081774 0.72 GAA (0.36) GAAPTK2BSMN1; SMN2
SCHEMBL12565976 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4251285-A1 HAIR COLORING COMPOSITIONS Wella International Operations Switzerland Sàrl (CH) 2023-10-04 EP claimed
WO-2022112473-A1 HAIR COLORING COMPOSITIONS WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) 2022-06-02 WO claimed
WO-2018031941-A1 HAIR COLORING COMPOSITION FOR PROVIDING A FILM ON KERATIN FIBERS NOXELL CORPORATION (US) 2018-02-15 WO claimed
WO-2018005641-A1 METHOD FOR COLORING HAIR FIBERS INTO A FIRST AND A SECOND PATTERNS NOXELL CORPORATION (US) 2018-01-04 WO claimed
WO-2017105832-A1 HAIR COLORING COMPOSITION COMPRISING ONE OR MORE ACRYLIC COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2017-06-22 WO claimed
WO-2017105833-A1 HAIR COLORING COMPOSITION COMPRISING ONE OR MORE ACRYLATE MONOMERS THE PROCTER & GAMBLE COMPANY (US) 2017-06-22 WO claimed
EP-1598047-B1 Composition for coloring of keratin fibres KPSS KAO GMBH (DE) 2011-11-30 EP claimed
US-20050257330-A1 Composition for coloring of keratin fibers KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2005-11-24 US claimed
EP-1598047-A1 Composition for coloring of keratin fibres KPSS-Kao Professional Salon Services GmbH (DE) 2005-11-23 EP claimed
CN-118714994-A Composition for lightening keratin fibers and method for lightening keratin fibers using the same 莱雅公司 2024-09-27 CN disclosed
EP-4247323-A2 GRANULATED HAIR DYE COMPOSITION Wella Germany GmbH (DE) 2023-09-27 EP disclosed
EP-3113754-B1 OXIDATIVE HAIR DYEING COMPOSITION KAO GERMANY GMBH (DE) 2022-07-27 EP disclosed
WO-2022106628-A2 GRANULATED HAIR DYE COMPOSITION WELLA GERMANY GMBH (DE) 2022-05-27 WO disclosed
EP-3941424-A1 HAIR COLORANT COMPOSITIONS Wella International Operations Switzerland Sàrl (CH) 2022-01-26 EP disclosed
US-20050257330-A1 Composition for coloring of keratin fibers KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2005-11-24 US disclosed
EP-1598047-A1 Composition for coloring of keratin fibres KPSS-Kao Professional Salon Services GmbH (DE) 2005-11-23 EP disclosed
EP-1242038-A2 AGENT FOR DYEING KERATIN CONTAINING FIBERS Henkel Kommanditgesellschaft auf Aktien (DE) 2002-09-25 EP disclosed
WO-2001047475-A2 AGENT FOR DYEING KERATIN CONTAINING FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-07-05 WO disclosed
EP-0618902-A1 PROCESS FOR PRODUCING 4,5-DIAMINO PYRAZOLE DERIVATIVES, THEIR USE FOR COLOURING HAIR AND NOVEL PYRAZOLE DERIVATIVES Wella Aktiengesellschaft (DE) 1994-10-12 EP disclosed
WO-1994008969-A1 PROCESS FOR PRODUCING 4,5-DIAMINO PYRAZOLE DERIVATIVES, THEIR USE FOR COLOURING HAIR AND NOVEL PYRAZOLE DERIVATIVES WELLA AKTIENGESELLSCHAFT (DE) 1994-04-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050257330-A1 Composition for coloring of keratin fibers KRT18, MT-CO3, CYB5R3 GAA 4857/4885PTK2B 2092/4885SMN1; SMN2 4665/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.