Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | MB | P02144 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | RARG | P13631 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21909284 | 0.86 | SMN1; SMN2 (0.52) | SMN1; SMN2HTTL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL3818227 | 0.84 | CA1 (0.50) | SMN1; SMN2HTTL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL11399811 | 0.81 | ALDH1A1 (0.50) | SMN1; SMN2HTTL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL11387426 | 0.79 | ALDH1A1 (0.47) | SMN1; SMN2HTTL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL6636363 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2HTTL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL9478167 | 0.78 | ALDH1A1 (0.46) | SMN1; SMN2HTTL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL25379946 | 0.76 | SMN1; SMN2 (0.53) | SMN1; SMN2HTTL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL861674 | 0.76 | SMN1; SMN2 (0.84) | SMN1; SMN2HTTL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL18793009 | 0.75 | SMN1; SMN2 (0.52) | SMN1; SMN2HTTL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL10922931 | 0.75 | NAPRT (0.62) | SMN1; SMN2HTTL3MBTL1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007084625-A2 | NOVEL COMPOUNDS AND METHODS FOR INHIBITING P53 ACTIVITY | MOUNT SINAI SCHOOL OF MEDICINE (US) | 2007-07-26 | — | — | WO | disclosed |