Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.46 |
| ▸ | MERTK | Q12866 | 6/20 | 0.45 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 2/20 | 0.43 |
| ▸ | ACP1 | P24666 | 2/20 | 0.43 |
| ▸ | OGG1 | O15527 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.42 |
| ▸ | GBA1 | P04062 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | WHR1 | P49842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14256546 | 0.85 | MERTK (0.51) | CXCR4MERTKAPPBCHEACHE | |
| SCHEMBL14256444 | 0.84 | MERTK (0.53) | CXCR4MERTKAPPBCHEACHE | |
| SCHEMBL14256699 | 0.83 | MERTK (0.52) | CXCR4MERTKAPPBCHEACHE | |
| SCHEMBL14256451 | 0.83 | MERTK (0.52) | CXCR4MERTKAPPBCHEACHE | |
| SCHEMBL14256450 | 0.81 | MERTK (0.52) | CXCR4MERTKAPPBCHEACHE | |
| SCHEMBL14468227 | 0.78 | MERTK (0.50) | CXCR4MERTKAPPBCHEACHE | |
| SCHEMBL27224041 | 0.76 | MERTK (0.61) | CXCR4MERTKAPPBCHEACHE | |
| SCHEMBL14256540 | 0.76 | MERTK (0.55) | CXCR4MERTKAPPBCHEACHE | |
| SCHEMBL14266722 | 0.76 | MERTK (0.55) | CXCR4MERTKAPPBCHEACHE | |
| SCHEMBL14256454 | 0.76 | MERTK (0.46) | CXCR4MERTKAPPBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007081978-A2 | MODULATORS OF HEPATOCYTE GROWTH FACTOR / C-MET ACTIVITY | ANGION BIOMEDICA CORPORATION (US) | 2007-07-19 | — | — | WO | disclosed |