Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 10/20 | 0.46 |
| ▸ | PPARG | P37231 | 9/20 | 0.46 |
| ▸ | PPARD | Q03181 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14468364 | 0.90 | HSD17B10 (0.42) | TARBP2PPARAPPARGPPARDHSD17B10 | |
| SCHEMBL14468450 | 0.86 | PPARG (0.39) | PPARAPPARGPPARDHSD17B10 | |
| SCHEMBL5378146 | 0.85 | TARBP2 (0.44) | TARBP2PPARAPPARGPPARDHSD17B10 | |
| SCHEMBL14468445 | 0.81 | TARBP2 (0.50) | TARBP2PPARAPPARGPPARDHSD17B10 | |
| SCHEMBL5374650 | 0.77 | HSD17B10 (0.39) | TARBP2PPARAPPARGPPARDHSD17B10 | |
| SCHEMBL14468329 | 0.77 | ALDH1A1 (0.45) | TARBP2PPARAPPARGPPARDHSD17B10 | |
| SCHEMBL5857375 | 0.76 | PPARA (0.67) | TARBP2PPARAPPARGPPARDHSD17B10 | |
| SCHEMBL5856086 | 0.74 | PPARA (0.56) | PPARAPPARGPPARDHSD17B10ALDH1A1 | |
| SCHEMBL5377994 | 0.74 | PPARA (0.47) | PPARAPPARGPPARDHSD17B10ALDH1A1 | |
| SCHEMBL5377489 | 0.73 | PPARG (0.37) | PPARAPPARGPPARDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241784-B2 | Carboxylic acid derivative and a pharmaceutical composition containing the derivative as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-07-10 | — | — | US | disclosed |