Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14543449 | 0.85 | ALDH1A1 (0.46) | ALDH1A1HSP90AA1MAPTNPC1RAB9A | |
| SCHEMBL31733261 | 0.84 | ALDH1A1 (0.49) | ALDH1A1HSP90AA1MAPTNPC1RAB9A | |
| SCHEMBL4497497 | 0.82 | ALDH1A1 (0.47) | ALDH1A1HSP90AA1MAPTNPC1RAB9A | |
| SCHEMBL14468617 | 0.75 | ALDH1A1 (0.46) | ALDH1A1HSP90AA1MAPTNPC1RAB9A | |
| SCHEMBL11453634 | 0.73 | MAPT (0.49) | ALDH1A1HSP90AA1MAPTNPC1KMT2A | |
| SCHEMBL4492478 | 0.73 | SMN1; SMN2 (0.45) | ALDH1A1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL1894132 | 0.72 | ALDH1A1 (0.50) | ALDH1A1HSP90AA1MAPTNPC1RAB9A | |
| SCHEMBL987100 | 0.72 | ALDH1A1 (0.50) | ALDH1A1HSP90AA1MAPTNPC1RAB9A | |
| SCHEMBL14609680 | 0.72 | KMT2A (0.49) | ALDH1A1HSP90AA1MAPTNPC1RAB9A | |
| SCHEMBL574989 | 0.71 | ALDH1A1 (0.49) | ALDH1A1HSP90AA1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070155777-A1 | Antiinflammation agents | AMGEN, INC. | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155777-A1 | Antiinflammation agents | TNF, NFATC1, NFKBIA | ALDH1A1 3037/4885HSP90AA1 462/4885MAPT 3631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.